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Melatonin Degradation The primary metabolic pathway of melatonin degradation involves hydroxylation by hepatic cytochrome P450 enzymes to form 6-hydroxymelatonin, which is subsequently conjugated with sulfate and excreted in the urine

Cum se utilizeaz Normcontrol

To this end, AR-positive CAFs from patients in Table 2 were pooled together to minimize data spread due to inter-individual variation, then co-cultured with LNCaP cells stably expressing GFP (GFP-LNCaP cells